Dominus is a leading pharmaceutical company, having HQ at Bangalore, India. At Dominus Healthcare, we are having diverse products across different therapeutic segments. We have established brands marketed across the Indian market. We are continuously achieving innovations to bring the new products into the market.

Telminus 20

Each tablet contains: Telmisartan 20 mg

Telminus 40

Each tablet contains: Telmisartan 40 mg

Tablets 

Telmisartan is a non-peptide ARB . Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE, kininase II). Angiotensin II is the principal pressor agent of the renin-angiotensin system (RAS), with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium. Telmisartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for angiotensin II synthesis.

There is also an angiotensin type 2 (AT2) receptor found in many tissues, but AT2 is not known to be associated with cardiovascular homeostasis. Telmisartan has much greater affinity (>3000-fold) for the AT1 receptor than for the AT2 receptor.

Telmisartan does not inhibit the ACE (kininase II) nor does it bind to or block other hormone receptors or ion channels known to be important in cardiovascular regulation.

Blockade of the angiotensin II receptor inhibits the negative regulatory feedback of angiotensin II on renin secretion, but the resulting increased plasma renin activity (PRA) and angiotensin II circulating levels do not overcome the effect of telmisartan on blood pressure.

10 Tablets in a strip

Telminus-40 telmisartan 40mg tablet